Viral cGAMP nuclease reveals the essential role of DNA sensing in protection against acute lethal virus infection
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DOI: 10.1126/sciadv.abb4565
Abstract: DNA sensing inhibition by viral cGAMP nuclease impairs anti-viral responses and protective immunity. Cells contain numerous immune sensors to detect virus infection. The cyclic GMP-AMP (cGAMP) synthase (cGAS) recognizes cytosolic DNA and activates innate immune… read more here.
Keywords: infection; cgamp nuclease; dna sensing; dna ... See more keywords