NBS1-CtIP–mediated DNA end resection suppresses cGAS binding to micronuclei
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DOI: 10.1093/nar/gkac079
Abstract: Abstract Cyclic guanosine monophosphate–adenosine monophosphate synthase (cGAS) is activated in cells with defective DNA damage repair and signaling (DDR) factors, but a direct role for DDR factors in regulating cGAS activation in response to micronuclear… read more here.
Keywords: dna; ctip; dna end; cgas binding ... See more keywords