Articles with "cgas dependent" as a keyword



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cGAS-dependent proinflammatory and immune homeostatic effects of the microtubule-targeting agent paclitaxel

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Published in 2023 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2023.1127623

Abstract: Taxanes are Microtubule-Targeting Agents (MTAs) that exert potent anticancer activity by directly killing cancer cells. However, recent evidence suggests that they may also stimulate inflammation and anticancer adaptive immunity and that these actions strongly contribute… read more here.

Keywords: microtubule targeting; immunity; dependent proinflammatory; cgas dependent ... See more keywords