A pan-cancer analysis of CpG Island gene regulation reveals extensive plasticity within Polycomb target genes
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DOI: 10.1038/s41467-021-22720-0
Abstract: CpG Island promoter genes make up more than half of human genes, and a subset regulated by Polycomb-Repressive Complex 2 (PRC2+-CGI) become DNA hypermethylated and silenced in cancer. Here, we perform a systematic analysis of… read more here.
Keywords: prc2 cgi; cpg island; cancer; cgi genes ... See more keywords