Genomic Loss and Epigenetic Silencing of the FOSL1 Tumor Suppressor Gene in Radiation-induced Neoplastic Transformation of Human CGL1 Cells Alters the Tumorigenic Phenotype In Vitro and In Vivo.
Sign Up to like & getrecommendations! Published in 2023 at "Radiation research"
DOI: 10.1667/rade-22-00216.1
Abstract: The CGL1 human hybrid cell system has been utilized for many decades as an excellent cellular tool for investigating neoplastic transformation. Substantial work has been done previously implicating genetic factors related to chromosome 11 to… read more here.
Keywords: gene; tumor suppressor; neoplastic transformation; radiation ... See more keywords
Identification of Radiation-Induced miRNA Biomarkers Using the CGL1 Cell Model System
Sign Up to like & getrecommendations! Published in 2022 at "Bioengineering"
DOI: 10.3390/bioengineering9050214
Abstract: MicroRNAs (miRNAs) have emerged as a potential class of biomolecules for diagnostic biomarker applications. miRNAs are small non-coding RNA molecules, produced and released by cells in response to various stimuli, that demonstrate remarkable stability in… read more here.
Keywords: cell; mirna biomarkers; induced mirna; radiation ... See more keywords