Articles with "cgmp katp" as a keyword



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The role of L-arginine/NO/cGMP/KATP channel pathway in the local antinociceptive effect of berberine in the rat formalin test.

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Published in 2023 at "Behavioural pharmacology"

DOI: 10.1097/fbp.0000000000000721

Abstract: Berberine is an isoquinoline alkaloid naturally produced by several types of plants. Berberine has extensive pharmacological effects, such as anti-diabetic, anti-inflammatory, and antioxidant effects. In the current study, we assess the antinociceptive effects of berberine… read more here.

Keywords: cgmp katp; formalin test; paw; berberine ... See more keywords
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The effect of montelukast, a leukotriene receptor antagonist, on the acetic acid-induced model of colitis in rats: Involvement of NO-cGMP-KATP channels pathway

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Published in 2022 at "Frontiers in Pharmacology"

DOI: 10.3389/fphar.2022.1011141

Abstract: Inflammatory bowel disease is a chronic autoimmune disorder that may involve entire gastrointestinal tract. The leukotrienes have a role as mediators in the pathophysiology of colitis. Here, we investigated the effect of a leukotriene receptor… read more here.

Keywords: cgmp katp; effect; montelukast; colitis ... See more keywords