Cyclo‐glycylproline attenuates hydrogen peroxide‐induced cellular damage mediated by the MDM2‐p53 pathway in human neural stem cells
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.30940
Abstract: Cyclo‐glycylproline (cGP), a cyclic dipeptide containing a condensation bond between glycine and proline, is produced by the cyclization of the N‐terminal tripeptide of insulin‐like growth factor‐1. Previous studies have shown that cGP administration exerts a… read more here.
Keywords: cgp; damage; oxidative stress; brain ... See more keywords
Dicalcium Phosphate Anhydrous: An Appropriate Bioceramic in Regeneration of Critical-Sized Radial Bone Defects in Rats
Sign Up to like & getrecommendations! Published in 2017 at "Calcified Tissue International"
DOI: 10.1007/s00223-017-0309-9
Abstract: The present study aimed to evaluate and compare the effectiveness of composites of calcium phosphates including β-tri calcium phosphate (β-TCP), dicalcium phosphate anhydrous (DCPA, monetite), mono-calcium phosphate monohydrate (MCPM), and hydroxyapatite (HA) with the chitosan-gelatin-platelet… read more here.
Keywords: cgp; cgp dcp; bone; tcp ... See more keywords
Challenges of Conducting Value Assessment for Comprehensive Genomic Profiling
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Technology Assessment in Health Care"
DOI: 10.1017/s026646232200040x
Abstract: Abstract Objectives Clinical practice is shifting toward an era of precision medicine. The use of comprehensive genomic profiling (CGP) in oncology has broad potential as a universal companion diagnostic for targeted therapies which may significantly… read more here.
Keywords: oncology; cgp; value assessment; assessment ... See more keywords
Cyanophycin Granule Polypeptide: a Neglected High Value-Added Biopolymer, Synthesized in Activated Sludge on a Large Scale
Sign Up to like & getrecommendations! Published in 2022 at "Applied and Environmental Microbiology"
DOI: 10.1128/aem.00742-22
Abstract: The conversion of organic pollutants into bioresources by activated sludge can reduce the carbon dioxide emission of wastewater treatment plants. Identification of new high value-added biopolymers produced by activated sludge is beneficial to recover bioresources.… read more here.
Keywords: cgp; high value; value added; sludge ... See more keywords
Abstract 654: Application of comprehensive genomic profiling (CGP) to predict therapeutic response to immune checkpoint inhibitors (ICI)
Sign Up to like & getrecommendations! Published in 2018 at "Cancer Research"
DOI: 10.1158/1538-7445.am2018-654
Abstract: Introduction : Immune check point inhibitors(ICIs) are widely used to treat various solid tumors, but there is a paucity of biomarkers that reliably predict response to such therapy. We sought to identify somatic alterations (SAs)… read more here.
Keywords: immune; cgp; response; response ici ... See more keywords
Primary adult retroperitoneal sarcoma (RS): Comprehensive genomic profiling (CGP) study.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2020.38.15_suppl.11541
Abstract: 11541Background: We performed CGP on 315 cases of RS to discover targetable genomic alterations (GA) and their potential impact on potential targeted and immunotherapy (IO) selection. Methods: FFPE... read more here.
Keywords: primary adult; cgp; comprehensive genomic; sarcoma comprehensive ... See more keywords
Primary tumor (p-bx) versus metastatic tumor (m-bx) tissue versus liquid biopsy (lb) in intrahepatic cholangiocarcinoma (IHCC): A comparative comprehensive genomic profiling (CGP) study.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2020.38.15_suppl.4579
Abstract: 4579Background: Genomic alterations (GA) characteristic of IHCC are well known. We queried whether GA from Pbx would differ from Mbx and Lbx in IHCC. Methods: Hybrid-capture based CGP was performed... read more here.
Keywords: tumor; cgp; versus metastatic; primary tumor ... See more keywords
Improvements in access to cancer clinical trials facilitated by comprehensive genomic profiling in non-small cell lung cancer.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2020.39.28_suppl.59
Abstract: 59 Background: The use of comprehensive genomic profiling (CGP) in cancer patients could lead to additional enrollment in clinical trials that study novel genetic biomarkers, potentially reducing treatment costs for payers and improving health outcomes… read more here.
Keywords: cgp; comprehensive genomic; additional clinical; clinical trials ... See more keywords
Comprehensive genomic profiling (CGP) utilizing cell-free DNA (cfDNA) in patients (pts) with pancreatic ductal adenocarcinoma (PDAC).
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2021.39.3_suppl.421
Abstract: 421Background: PDAC has a propensity for early systemic dissemination and most pts with primary tumors radiographically confined to the pancreas harbor micro-metastases. cfDNA based CGP offers a no... read more here.
Keywords: genomic profiling; cgp utilizing; utilizing cell; profiling cgp ... See more keywords
Sarcomatoid (srcRCC) versus clear cell (ccRCC) renal cell carcinoma: A comparative comprehensive genomic profiling (CGP) study.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2021.39.6_suppl.349
Abstract: 349Background: srcRCC is a well-described histologic entity often featuring rapid progression and aggressive clinical course when compared with classic ccRCC. We queried whether CGP would uncover o... read more here.
Keywords: sarcomatoid srcrcc; clear cell; cgp; cell ... See more keywords
Comprehensive genomic profiling (CGP) to reveal new opportunities and challenges in muscle-invasive bladder cancer (MIBC).
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2021.39.6_suppl.479
Abstract: 479Background: MIBC is an aggressive disease and a limited number of patients (pts) will benefit from neoadjuvant chemotherapy (NAC) or immunotherapy. CGP may help identify prognostic factors, pred... read more here.
Keywords: genomic profiling; reveal new; cgp reveal; profiling cgp ... See more keywords