Articles with "cgs 21680" as a keyword



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The adenosine A(2A) receptor agonist CGS 21680 alleviates auditory sensorimotor gating deficits and increases in accumbal CREB in rats neonatally treated with quinpirole

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Published in 2020 at "Psychopharmacology"

DOI: 10.1007/s00213-020-05631-8

Abstract: The adenosine A(2A) receptor forms a mutually inhibitory heteromer with the dopamine D2 receptor, and A(2A) agonists decrease D2 signaling. This study analyzed whether an adenosine A(2A) agonist would alleviate deficits in sensorimotor gating and… read more here.

Keywords: agonist; sensorimotor gating; cgs 21680; adenosine receptor ... See more keywords

Early tyrosine phosphorylation events following adenosine A2A receptor in human neutrophils: identification of regulated pathways

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Published in 2017 at "Journal of Leukocyte Biology"

DOI: 10.1189/jlb.2vma1216-517r

Abstract: Activation of the adenosine 2A receptor (A2AR) elevates intracellular levels of cAMP and acts as a physiologic inhibitor of inflammatory neutrophil functions. In this study, we looked into the impact of A2AR engagement on early… read more here.

Keywords: tyrosine phosphorylation; cgs 21680; phosphorylation events; receptor ... See more keywords