Intrinsic GTPase activity of a ribosomal maturation protein CgtA is associated with its inter-domain movement: insights from MD simulations and biochemical studies
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Biomolecular Structure and Dynamics"
DOI: 10.1080/07391102.2016.1224732
Abstract: CgtA is an essential ribosome associated GTPase protein of bacteria. It has three domains, viz., Obg, GTPase, and C-terminal domain. It is a multifunctional protein and it is being considered as a potential drug target… read more here.
Keywords: protein; cgta; gtpase activity; gtpase ... See more keywords
Knockdown Experiment Reveals an Essential GTPase CgtA’s Involvement in Growth, Viability, Motility, Morphology, and Persister Phenotypes in Vibrio cholerae
Sign Up to like & getrecommendations! Published in 2023 at "Microbiology Spectrum"
DOI: 10.1128/spectrum.03181-22
Abstract: It is very important that we must find new drug target proteins from multidrug-resistant human-pathogenic organisms like V. cholerae. CgtA is among such potential candidates, and here, we are reporting about some newly identified cellular… read more here.
Keywords: cholerae; growth viability; motility morphology; viability motility ... See more keywords