Hinge-Deficient IgG1 Fc Fusion: Application to Human Lactoferrin.
Sign Up to like & getrecommendations! Published in 2017 at "Molecular pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.7b00221
Abstract: Fusion of therapeutic proteins with the antibody Fc domain is a strategy widely applied to increase protein half-life in plasma. In our previous study, we generated a recombinant human lactoferrin (hLF)-immunoglobulin G1 Fc fusion protein… read more here.
Keywords: hinge; ch2 ch3; hlf; fusion ... See more keywords
Changes in molecular film metallicity with minor modifications of the constitutive quinonoid zwitterions
Sign Up to like & getrecommendations! Published in 2017 at "RSC Advances"
DOI: 10.1039/c7ra01597f
Abstract: Molecular films of quinonoid zwitterions, of the general formula C6H2(O)2(NHR)2, have been shown to display electronic properties highly dependent on the nature of the N-substituent R when deposited on gold substrates. The different spacing and… read more here.
Keywords: quinonoid zwitterions; ch2; ch2 ch2; film ... See more keywords
Breakdown curves of CH2(+), CH3(+), and CH4(+) molecules
Sign Up to like & getrecommendations! Published in 2020 at "Astronomy and Astrophysics"
DOI: 10.1051/0004-6361/202037926
Abstract: Aims. The aim of this work is to provide semi-empirical branching ratios (BRs) for the kinetic databases used in astrochemistry, such as the KInetic Database for Astrochemistry (KIDA). Our work focuses on the CHy(+) species… read more here.
Keywords: breakdown curves; curves ch2; chemical; ch3 ch4 ... See more keywords
Turning the tables on cytomegalovirus: targeting viral Fc receptors by CARs containing mutated CH2–CH3 IgG spacer domains
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Translational Medicine"
DOI: 10.1186/s12967-018-1394-x
Abstract: BackgroundDuring infection with human cytomegalovirus (HCMV) several viral proteins occur on cell surfaces in high quantity. We thus pursue an HLA-independent approach for immunotherapy of HCMV using chimeric antigen receptors (CARs) and bispecific BiTE® antibody… read more here.
Keywords: igg; ch3; hcmv; ch2 ch3 ... See more keywords