A comparative computational mechanistic study on derivatives of pyriplatin, modified with the –CH2Ph3P+ group, as anticancer complexes targeting mitochondria
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DOI: 10.1016/j.ica.2020.119863
Abstract: Abstract Chemoresistance of Pt(II) based therapy is related to the extensive repair of modified DNA in the nucleus as a consequence of the nucleotide excision repair mechanism. Delivering Pt(II) complexes to the mitochondria to attack… read more here.
Keywords: ch2ph3p group; computational mechanistic; mechanistic study; ch2ph3p ... See more keywords