First-dose ChAdOx1 and BNT162b2 COVID-19 vaccines and thrombocytopenic, thromboembolic and hemorrhagic events in Scotland
Sign Up to like & getrecommendations! Published in 2021 at "Nature Medicine"
DOI: 10.1038/s41591-021-01408-4
Abstract: Reports of ChAdOx1 vaccine–associated thrombocytopenia and vascular adverse events have led to some countries restricting its use. Using a national prospective cohort, we estimated associations between exposure to first-dose ChAdOx1 or BNT162b2 vaccination and hematological… read more here.
Keywords: first dose; chadox1; thromboembolic hemorrhagic; dose chadox1 ... See more keywords
Impact of vaccination on new SARS-CoV-2 infections in the United Kingdom
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DOI: 10.1038/s41591-021-01410-w
Abstract: The effectiveness of COVID-19 vaccination in preventing new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections in the general community is still unclear. Here, we used the Office for National Statistics COVID-19 Infection Survey—a large… read more here.
Keywords: cov infections; chadox1; united kingdom; sars cov ... See more keywords
A case of myocarditis following ChAdOx1 nCov-19 vaccination
Sign Up to like & getrecommendations! Published in 2022 at "Acta Cardiologica"
DOI: 10.1080/00015385.2022.2040825
Abstract: Abstract Introduction: Myocarditis is an inflammatory disease of the myocardium, that might lead to reduced cardiac function and in the most severe cases to mortality. Although uncommon, it is a known adverse event after vaccination… read more here.
Keywords: myocarditis; vaccination; chadox1; myocarditis following ... See more keywords
Homologous and Heterologous Boosting of the Chadox1-S1-S COVID-19 Vaccine With the SCB-2019 Vaccine Candidate: A Randomized, Controlled, Phase 2 Study
Sign Up to like & getrecommendations! Published in 2022 at "Open Forum Infectious Diseases"
DOI: 10.1093/ofid/ofac418
Abstract: Abstract Background Ongoing outbreaks of coronavirus disease 2019 (COVID-19) are driven by waning immunity following primary immunizations and emergence of new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants that escape vaccine-induced neutralizing antibodies. It… read more here.
Keywords: chadox1; vaccine scb; 2019 vaccine; scb 2019 ... See more keywords
Cutaneous reactions to inactivated SARS‐CoV‐2 vaccine and ChAdOx1‐S (recombinant) vaccine against SARS‐CoV‐2: a case series from the Philippines
Sign Up to like & getrecommendations! Published in 2021 at "Journal of the European Academy of Dermatology and Venereology"
DOI: 10.1111/jdv.17575
Abstract: The Philippines remains one of the countries with the highest number of new COVID-19 cases in the Western Pacific region. The Philippine government granted emergency use authorizations for inactivated SARS-COV-2 (Sinovac) and recombinant ChAdOx1-S (AstraZeneca)… read more here.
Keywords: chadox1; vaccine; sars cov; reactions inactivated ... See more keywords
CMV-associated T cell and NK cell terminal differentiation does not impact immunogenicity of ChAdOx1 vaccination.
Sign Up to like & getrecommendations! Published in 2022 at "JCI insight"
DOI: 10.1172/jci.insight.154187
Abstract: Cytomegalovirus (CMV) is a globally ubiquitous pathogen with a seroprevalence of approximately 50% in the UK. CMV infection induces expansion of immunosenescent T cell and NK cell populations with these cells demonstrating lower responsiveness to… read more here.
Keywords: cmv associated; vaccination; cell; cell cell ... See more keywords
A single-dose ChAdOx1-vectored vaccine provides complete protection against Nipah Bangladesh and Malaysia in Syrian golden hamsters
Sign Up to like & getrecommendations! Published in 2019 at "PLoS Neglected Tropical Diseases"
DOI: 10.1371/journal.pntd.0007462
Abstract: Nipah virus (NiV) is a highly pathogenic re-emerging virus that causes outbreaks in South East Asia. Currently, no approved and licensed vaccine or antivirals exist. Here, we investigated the efficacy of ChAdOx1 NiVB, a simian… read more here.
Keywords: protection; chadox1; chadox1 nivb; dose chadox1 ... See more keywords
COVID-19 vaccine type-dependent differences in immunogenicity and inflammatory response: BNT162b2 and ChAdOx1 nCoV-19
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.975363
Abstract: Evaluation of the safety and immunogenicity of new vaccine platforms is needed to increase public acceptance of coronavirus disease 2019 (COVID-19) vaccines. Here, we evaluated the association between reactogenicity and immunogenicity in healthy adults following… read more here.
Keywords: chadox1 ncov; chadox1; immunogenicity; bnt162b2 chadox1 ... See more keywords
Identification of genes related to immune enhancement caused by heterologous ChAdOx1–BNT162b2 vaccines in lymphocytes at single-cell resolution with machine learning methods
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2023.1131051
Abstract: The widely used ChAdOx1 nCoV-19 (ChAd) vector and BNT162b2 (BNT) mRNA vaccines have been shown to induce robust immune responses. Recent studies demonstrated that the immune responses of people who received one dose of ChAdOx1… read more here.
Keywords: cell; chadox1; feature; heterologous chadox1 ... See more keywords
Identification of dynamic gene expression profiles during sequential vaccination with ChAdOx1/BNT162b2 using machine learning methods
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2023.1138674
Abstract: To date, COVID-19 remains a serious global public health problem. Vaccination against SARS-CoV-2 has been adopted by many countries as an effective coping strategy. The strength of the body’s immune response in the face of… read more here.
Keywords: vaccination; chadox1; machine learning; bnt162b2 ... See more keywords
Evaluation of Two-Month Antibody Levels after Heterologous ChAdOx1-S/BNT162b2 Vaccination Compared to Homologous ChAdOx1-S or BNT162b2 Vaccination
Sign Up to like & getrecommendations! Published in 2022 at "Vaccines"
DOI: 10.3390/vaccines10040491
Abstract: We evaluated the post-vaccination humoral response of three real-world cohorts. Vaccinated subjects primed with ChAdOx1-S and boosted with BNT162b2 mRNA vaccine were compared to homologous dosing (BNT162b2/BNT162b2 and ChAdOx1-S/ChAdOx1-S). Serum samples were collected two months… read more here.
Keywords: chadox1; bnt162b2; chadox1 bnt162b2; compared homologous ... See more keywords