Molecular fillers for increasing the refractive index of polystyrene hybrids by chain assembly at polyhedral oligomeric silsesquioxane
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DOI: 10.1038/s41428-019-0302-4
Abstract: We developed a molecular filler based on polyhedral oligomeric silsesquioxane (POSS) containing halogenated aromatic substituents to increase the refractive indices (RIs) of polystyrene (PS). PS hybrid films with a series of POSS derivatives were prepared… read more here.
Keywords: chain assembly; oligomeric silsesquioxane; polyhedral oligomeric; filler ... See more keywords
Characterization and optimization of two-chain folding pathways of insulin via native chain assembly
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DOI: 10.1038/s42004-018-0024-0
Abstract: Until recently the total synthesis of insulin, with its characteristic heterodimeric structure crosslinked by two interchain and one intrachain disulfide (SS) bridge, remained largely an unsolved challenge. By optimizing the synthesis and directed disulfide crosslinking… read more here.
Keywords: insulin; chain; folding pathways; pathways insulin ... See more keywords
Mechanistic insights into the subversion of the linear ubiquitin chain assembly complex by the E3 ligase IpaH1.4 of Shigella flexneri
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DOI: 10.1073/pnas.2116776119
Abstract: Significance Shigella flexneri, a deleterious bacterium, causes massive human infection cases and deaths worldwide. To facilitate survival and replication in infected host cells, S. flexneri can secrete two highly similar E3 ligase effectors, IpaH1.4 and… read more here.
Keywords: chain assembly; shigella flexneri; ubiquitin chain; assembly complex ... See more keywords