Construction of polymethine chain-modified pentamethylene cyanine dyes for G-quadruplex imaging in live cells.
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DOI: 10.1039/d5cc00436e
Abstract: Here, a supramolecular strategy that relies on the G-quadruplex DNA recognition-driven disaggregation of pentamethylene cyanine Cy5-ph-H aggregates is outlined, which can turn on its fluorescence and be used to visualize G-quadruplex DNA in living cells… read more here.
Keywords: construction polymethine; pentamethylene cyanine; polymethine chain; cyanine dyes ... See more keywords
Synthesis of Side-Chain Modified Peptides Using Iterative Solid Phase ‘Click’ Methodology
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DOI: 10.1071/ch16567
Abstract: A series of side-chain modified peptides have been prepared via an iterative sequence of peptide couplings and azide–alkyne cycloadditions (‘click’ reactions) using Fmoc-solid phase peptide synthesis. This efficient modular synthetic route allows the systematic and… read more here.
Keywords: chain modified; methodology; side chain; modified peptides ... See more keywords