PLRP2 selectively localizes synaptic membrane proteins via acyl-chain remodeling of phospholipids
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Lipid Research"
DOI: 10.1194/jlr.ra120001087
Abstract: The plasma membrane of neurons consists of distinct domains, each of which carries specialized functions and a characteristic set of membrane proteins. While this compartmentalized membrane organization is essential for neuronal functions, it remains controversial… read more here.
Keywords: membrane proteins; acyl chain; membrane; chain remodeling ... See more keywords
Brain and serum lipidomic profiles implicate Lands cycle acyl chain remodeling association with APOEε4 and mild cognitive impairment
Sign Up to like & getrecommendations! Published in 2024 at "Frontiers in Aging Neuroscience"
DOI: 10.3389/fnagi.2024.1419253
Abstract: Introduction At least one-third of the identified risk alleles from Genome-Wide Association Studies (GWAS) of Alzheimer’s disease (AD) are involved in lipid metabolism, lipid transport, or direct lipid binding. In fact, a common genetic variant… read more here.
Keywords: acyl chain; cycle acyl; lands cycle; association ... See more keywords