Chain-Shortened Myostatin Inhibitory Peptides Improve Grip Strength in Mice.
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DOI: 10.1021/acsmedchemlett.9b00174
Abstract: Inhibition of myostatin is a promising strategy for treatment of muscle atrophic disorders. We had already identified a 23-mer peptide (1) as a synthetic myostatin inhibitor, and structure-activity relationship studies with 1 afforded a potent… read more here.
Keywords: grip strength; myostatin inhibitory; chain shortened;