Modulation of the 5-Lipoxygenase Pathway by Chalcogen-Containing Inhibitors of Leukotriene A4 Hydrolase
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DOI: 10.3390/ijms24087539
Abstract: The 5-lipoxygenase (5-LOX) pathway gives rise to bioactive inflammatory lipid mediators, such as leukotrienes (LTs). 5-LOX carries out the oxygenation of arachidonic acid to the 5-hydroperoxy derivative and then to the leukotriene A4 epoxide which… read more here.
Keywords: leukotriene hydrolase; chalcogen containing; activity; containing inhibitors ... See more keywords