Identification of a Prenyl Chalcone as a Competitive Lipoxygenase Inhibitor: Screening, Biochemical Evaluation and Molecular Modeling Studies
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DOI: 10.3390/molecules26082205
Abstract: Cyclooxygenase (COX) and lipoxygenase (LOX) are key targets for the development of new anti-inflammatory agents. LOX, which is involved in the biosynthesis of mediators in inflammation and allergic reactions, was selected for a biochemical screening… read more here.
Keywords: lipoxygenase; molecular modeling; chalcone competitive; inhibitor ... See more keywords