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   Articles with "challenge" as a keyword



Understanding Titin Variants in the Age of Next-Generation Sequencing-A Titanic Challenge.

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recommendations! Published in 2018 at "JAMA neurology"

DOI: 10.1001/jamaneurol.2017.3068

Abstract: The titin gene (TTN), with its 364 exons, encodes the largest human protein. It gives rise to a dizzying array of alternatively spliced isoforms differentially expressed in various skeletal muscles, heart, and in development. Titin… read more here.

Keywords: challenge; ttn; gene; next generation ... See more keywords

Enabling Single-Challenge Multichannel-Response OPUFs: Adaptive Nanofilms from Aggregation-Controlled Multicolor Carbon Dots.

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recommendations! Published in 2025 at "Advanced materials"

DOI: 10.1002/adma.202519060

Abstract: Optical physical unclonable functions (OPUFs) provide a powerful and advanced anti-counterfeiting solution by harnessing inherent random physical features. However, achieving a balance among multichannel unclonability, scalability, and non-destructive implementation remains a significant challenge. This study… read more here.

Keywords: multichannel response; carbon dots; challenge multichannel; single challenge ... See more keywords

Safety of COVID‐19 vaccination in children with prior allergic reactions or mast cell disorders

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recommendations! Published in 2023 at "Clinical and Translational Allergy"

DOI: 10.1002/clt2.12267

Abstract: To the editor, Over 13 billion Coronavirus disease 2019 (COVID‐19) vaccines have been administered worldwide. However, there is a lack of evidence‐ based guidance on the management of children with reported allergic reactions to the… read more here.

Keywords: allergic reactions; covid; mast cell; skin testing ... See more keywords

GABAergic signaling in human and murine NK cells upon challenge with Toxoplasma gondii

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recommendations! Published in 2021 at "Journal of Leukocyte Biology"

DOI: 10.1002/jlb.3hi0720-431r

Abstract: Protective cytotoxic and proinflammatory cytokine responses by NK cells impact the outcome of infections by Toxoplasma gondii, a common parasite in humans and other vertebrates. However, T. gondii can also sequester within NK cells and… read more here.

Keywords: gaba; toxoplasma gondii; human murine; gondii ... See more keywords

Long‐Lasting Protection and Dose Optimization of MPXV Polyvalent Mpox mRNA Vaccines Against Lethal Vaccinia Virus Challenge in Mice

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recommendations! Published in 2024 at "Journal of Medical Virology"

DOI: 10.1002/jmv.70143

Abstract: The outbreak of clade II monkeypox virus (MPXV) and the additional outbreak in Central Africa of clade I virus from 2023 have attracted worldwide attention. The development of a scalable and effective vaccine against the… read more here.

Keywords: protection; virus; challenge; mrna vaccines ... See more keywords
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CG‐SENSE revisited: Results from the first ISMRM reproducibility challenge

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recommendations! Published in 2020 at "Magnetic Resonance in Medicine"

DOI: 10.1002/mrm.28569

Abstract: The aim of this work is to shed light on the issue of reproducibility in MR image reconstruction in the context of a challenge. Participants had to recreate the results of “Advances in sensitivity encoding… read more here.

Keywords: first ismrm; sense revisited; challenge; reproducibility ... See more keywords

Pandemic vaccine testing: Combining conventional and challenge studies

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recommendations! Published in 2022 at "Pharmacoepidemiology and Drug Safety"

DOI: 10.1002/pds.5429

Abstract: Early into COVID, human challenge trials were considered, but usually as alternatives to conventional randomized controlled trials. Instead, assessment of authorized COVID vaccines, of further COVID vaccines, and of vaccines against future pandemics should combine… read more here.

Keywords: testing combining; conventional challenge; combining conventional; pandemic vaccine ... See more keywords

The Hydrogen-Storage Challenge: Nanoparticles for Metal-Catalyzed Ammonia Borane Dehydrogenation.

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recommendations! Published in 2021 at "Small"

DOI: 10.1002/smll.202102759

Abstract: Dihydrogen is one of the sustainable energy vectors envisioned for the future. However, the rapidly reversible and secure storage of large quantities of hydrogen is still a technological and scientific challenge. In this context, this… read more here.

Keywords: storage; ammonia borane; challenge; hydrogen ... See more keywords

Oral challenge vs routine care to assess low-risk penicillin allergy in critically ill hospital patients (ORACLE): a pilot safety and feasibility randomised controlled trial

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recommendations! Published in 2024 at "Intensive Care Medicine"

DOI: 10.1007/s00134-024-07448-x

Abstract: Critically ill patients are vulnerable to penicillin allergy labels that may be incorrect. The validity of skin testing in intensive care units (ICUs) is uncertain. Many penicillin allergy labels are low risk, and validated tools… read more here.

Keywords: low risk; risk penicillin; penicillin; challenge ... See more keywords

Highlight report: Mycotoxins as food contaminants in Africa—challenges and perspectives

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recommendations! Published in 2018 at "Archives of Toxicology"

DOI: 10.1007/s00204-018-2203-2

Abstract: In 2050, the world population is expected to amount to 9.8 people (DESA 2015). Especially on the African continent, the population is increasing. This fact causes a food challenge which has to be faced in… read more here.

Keywords: mycotoxins food; challenge; report mycotoxins; food contaminants ... See more keywords

Measurement uncertainty challenge

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recommendations! Published in 2017 at "Analytical and Bioanalytical Chemistry"

DOI: 10.1007/s00216-017-0210-4

Abstract: We would like to invite you to participate in the Analytical Challenge, a series of puzzles to entertain and challenge our readers. This special feature of “Analytical and Bioanalytical Chemistry” (ABC) has established itself as… read more here.

Keywords: challenge; bioanalytical chemistry; analytical bioanalytical; chemistry ... See more keywords