Human challenge models: tools to accelerate the development of malaria vaccines
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DOI: 10.1080/14760584.2019.1580577
Abstract: ABSTRACT Introduction: Malaria challenge models, where healthy human volunteers are intentionally infected with Plasmodium species parasites under controlled conditions, can be undertaken in several well-defined ways. These challenge models enable evaluation of the kinetics of… read more here.
Keywords: challenge models; malaria vaccines; human challenge; development ... See more keywords
Controlled Human Infection Models To Accelerate Vaccine Development
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DOI: 10.1128/cmr.00008-21
Abstract: The timelines for developing vaccines against infectious diseases are lengthy, and often vaccines that reach the stage of large phase 3 field trials fail to provide the desired level of protective efficacy. The application of… read more here.
Keywords: controlled human; development; infection; human challenge ... See more keywords