Key criteria for the ethical acceptability of COVID-19 human challenge studies: Report of a WHO Working Group
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DOI: 10.1016/j.vaccine.2020.10.075
Abstract: This report of WHO Working Group for Guidance on Human Challenge Studies in COVID-19 outlines ethical standards for COVID-19 challenge studies. It includes eight Key Criteria related to scientific justification, risk-benefit assessment, consultation and engagement,… read more here.
Keywords: working group; challenge; challenge studies; human challenge ... See more keywords
Re-challenge Studies in Non-celiac Gluten Sensitivity: A Systematic Review and Meta-Analysis
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DOI: 10.3389/fphys.2017.00621
Abstract: Background: Non-celiac gluten sensitivity (NCGS) is a clinical entity characterized by intestinal and/or extra-intestinal symptoms related to the ingestion of gluten in individuals that are not affected by either celiac disease (CD) or wheat allergy… read more here.
Keywords: challenge studies; gluten challenge; challenge; meta analysis ... See more keywords
Selection of Surrogate Bacteria for Use in Food Safety Challenge Studies: A Review.
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DOI: 10.4315/0362-028x.jfp-16-536
Abstract: Nonpathogenic surrogate bacteria are prevalently used in a variety of food challenge studies in place of foodborne pathogens such as Listeria monocytogenes, Salmonella, Escherichia coli O157:H7, and Clostridium botulinum because of safety and sanitary concerns.… read more here.
Keywords: challenge studies; surrogate; given conditions; surrogate bacteria ... See more keywords