PvDBPII elicits multiple antibody-mediated mechanisms that reduce growth in a Plasmodium vivax challenge trial
Sign Up to like & getrecommendations! Published in 2024 at "NPJ Vaccines"
DOI: 10.1038/s41541-023-00796-7
Abstract: The receptor-binding domain, region II, of the Plasmodium vivax Duffy binding protein (PvDBPII) binds the Duffy antigen on the reticulocyte surface to mediate invasion. A heterologous vaccine challenge trial recently showed that a delayed dosing… read more here.
Keywords: vivax; antibody; challenge trial; pvdbpii ... See more keywords
The case for development of a core outcome set (COS) and supplemental reporting guidelines for influenza vaccine challenge trial research in swine
Sign Up to like & getrecommendations! Published in 2025 at "Frontiers in Veterinary Science"
DOI: 10.3389/fvets.2025.1465926
Abstract: Previously, we systematically reviewed more than 20 years of influenza vaccine challenge trial research in pigs to answer the question, “does vaccinating sows protect offspring?” Overall, most studies were well designed but clinical heterogeneity made between-study… read more here.
Keywords: influenza vaccine; challenge trial; vaccine challenge; research ... See more keywords