SARS-CoV-2 Delta variant induces enhanced pathology and inflammatory responses in K18-hACE2 mice
Sign Up to like & getrecommendations! Published in 2022 at "PLoS ONE"
DOI: 10.1371/journal.pone.0273430
Abstract: The COVID-19 pandemic has been fueled by novel variants of concern (VOC) that have increased transmissibility, receptor binding affinity, and other properties that enhance disease. The goal of this study is to characterize unique pathogenesis… read more here.
Keywords: k18 hace2; delta; pathology; delta variant ... See more keywords
Frequency‐dependent airway hyperresponsiveness in a mouse model of emphysema and allergic inflammation
Sign Up to like & getrecommendations! Published in 2018 at "Physiological Reports"
DOI: 10.14814/phy2.13568
Abstract: Asthma and chronic obstructive pulmonary disease (COPD), chronic airway inflammatory diseases characterized by airflow limitation, have different etiologies and pathophysiologies. Asthma–COPD Overlap (ACO) has recently been used for patients with mixed asthma and COPD. The… read more here.
Keywords: ova challenged; deficient; challenged mice; model ... See more keywords
Short‐term semaglutide treatment improves FGF21 responsiveness in primary hepatocytes isolated from high fat diet challenged mice
Sign Up to like & getrecommendations! Published in 2023 at "Physiological Reports"
DOI: 10.14814/phy2.15620
Abstract: Metabolic functions of GLP‐1 and its analogues have been extensively investigated. In addition to acting as an incretin and reducing body weight, we and others have suggested the existence of GLP‐1/fibroblast growth factor 21 (FGF21)… read more here.
Keywords: treatment improves; primary hepatocytes; fgf21; semaglutide treatment ... See more keywords
Lonicerae Japonicae Flos Extract Promotes Sleep in Sleep-Deprived and Lipopolysaccharide-Challenged Mice
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Neuroscience"
DOI: 10.3389/fnins.2022.848588
Abstract: Lonicerae Japonicae Flos (LJF) is commonly used in Chinese herbal medicines and exhibits anti-viral, anti-oxidative, and anti-inflammatory properties. The reciprocal relationship between sleep, the immune system and the central nervous system is well-established in the… read more here.
Keywords: sleep; sleep deprivation; lonicerae japonicae; mice ... See more keywords
Effects of Blidingia sp. Extract on Intestinal Inflammation and Microbiota Composition in LPS-Challenged Mice
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2019.00763
Abstract: Blidingia sp. is a green alga that has spread rapidly in Subei Shoal, China. To explore the potential beneficial effects of Blidingia sp., we investigated the anti-inflammatory activity of its water–methanol extract of Blidingia sp.… read more here.
Keywords: challenged mice; intestinal inflammation; composition; lps challenged ... See more keywords