Strategies for Interference of Insulin Fibrillogenesis: Challenges and Advances
Sign Up to like & getrecommendations! Published in 2022 at "ChemBioChem"
DOI: 10.1002/cbic.202100678
Abstract: The discovery of insulin came with very high hopes for diabetic patients. In 2021, the world celebrated the 100th anniversary of the discovery of this vital hormone. However, external use of insulin is highly affected… read more here.
Keywords: insulin fibrillogenesis; challenges advances; fibrillogenesis challenges; interference insulin ... See more keywords
Challenges and Advances in SLE Autoantibody Detection and Interpretation
Sign Up to like & getrecommendations! Published in 2019 at "Current Treatment Options in Rheumatology"
DOI: 10.1007/s40674-019-00122-0
Abstract: Purpose of reviewThis review is an overview of key autoantibodies used in the diagnosis and management of SLE. Questions addressed are the advantages to but limitations of ANA testing and what are the key considerations… read more here.
Keywords: autoantibody detection; sle autoantibody; sle; advances sle ... See more keywords
Challenges and advances towards the rational design of microalgal synthetic promoters in Chlamydomonas reinhardtii.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of experimental botany"
DOI: 10.1093/jxb/erad100
Abstract: Microalgae hold the enormous potential to provide a safe and sustainable source of high-value compounds, acting as carbon-fixing biofactories that could help to mitigate rapidly progressing climate change. Bioengineering microalgal strains will be key to… read more here.
Keywords: challenges advances; rational design; chlamydomonas reinhardtii; synthetic promoters ... See more keywords
Molecular Docking: Challenges, Advances and its Use in Drug Discovery Perspective.
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DOI: 10.2174/1389450119666181022153016
Abstract: Molecular docking is a process through which small molecules are docked into the macromolecular structures for scoring its complementary values at the binding sites. It is a vibrant research area with dynamic utility in structure-based… read more here.
Keywords: advances use; drug designing; drug; challenges advances ... See more keywords
Challenges and Advances in Gene Therapy Approaches for Neurodegenerative Disorders.
Sign Up to like & getrecommendations! Published in 2017 at "Current gene therapy"
DOI: 10.2174/1566523217666171013124150
Abstract: INTRODUCTION The recent approval of Spinraza (nusinersen), an antisense oligonucleotide, by U.S. Food and Drug Administration to treat patients with spinal muscular atrophy, has reignited interests of researchers in designing and testing new gene therapy… read more here.
Keywords: gene therapy; therapy approaches; therapy; challenges advances ... See more keywords
Alagille Syndrome: Diagnostic Challenges and Advances in Management
Sign Up to like & getrecommendations! Published in 2020 at "Diagnostics"
DOI: 10.3390/diagnostics10110907
Abstract: Alagille syndrome (ALGS) is a multisystem disease characterized by cholestasis and bile duct paucity on liver biopsy in addition to variable involvement of the heart, eyes, skeleton, face, kidneys, and vasculature. The identification of JAG1… read more here.
Keywords: advances management; diagnostic challenges; alagille syndrome; management ... See more keywords