Fundamental challenges to the development of a preventive HIV vaccine.
Sign Up to like & getrecommendations! Published in 2018 at "Current opinion in virology"
DOI: 10.1016/j.coviro.2018.02.004
Abstract: There is consensus that only a preventive vaccine can contain the HIV/AIDS pandemic. After 30 years still there is no preventive HIV vaccine. This article examines fundamental challenges to the development of a preventive HIV… read more here.
Keywords: fundamental challenges; hiv; challenges development; vaccine ... See more keywords
Challenges in the development of chronic pulmonary hypertension models in large animals
Sign Up to like & getrecommendations! Published in 2017 at "Pulmonary Circulation"
DOI: 10.1086/690099
Abstract: Pulmonary hypertension (PH) results in significant morbidity and mortality. Chronic PH animal models may advance the study of PH’s mechanisms, evolution, and therapy. In this report, we describe the challenges and successes in developing three… read more here.
Keywords: large animals; pulmonary hypertension; model; challenges development ... See more keywords
Challenges on the Development of Biodiversity Biobanks: The Living Archives of Biodiversity.
Sign Up to like & getrecommendations! Published in 2022 at "Biopreservation and biobanking"
DOI: 10.1089/bio.2021.0127
Abstract: Biodiversity biobanks or ex situ biodiversity biorepositories tend to receive less attention compared with their biomedical counterparts. In this review, we highlight the necessity for these biorepositories by presenting their significant role in health, biodiversity,… read more here.
Keywords: biobanks living; challenges development; biodiversity biobanks; biodiversity ... See more keywords
Challenges for the development of a universal vaccine against leptospirosis revealed by the evaluation of 22 vaccine candidates
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2022.940966
Abstract: Leptospirosis is a neglected disease of man and animals that affects nearly half a million people annually and causes considerable economic losses. Current human vaccines are inactivated whole-cell preparations (bacterins) of Leptospira spp. that provide… read more here.
Keywords: evaluation; development universal; universal vaccine; leptospirosis ... See more keywords
Senecavirus A as an Oncolytic Virus: Prospects, Challenges and Development Directions
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.839536
Abstract: Oncolytic viruses have the capacity to selectively kill infected tumor cells and trigger protective immunity. As such, oncolytic virotherapy has become a promising immunotherapy strategy against cancer. A variety of viruses from different families have… read more here.
Keywords: oncolytic virus; development; virus prospects; senecavirus oncolytic ... See more keywords
Challenges to the development of the trauma system in Egypt
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Public Health in Africa"
DOI: 10.4081/jphia.2023.2214
Abstract: Trauma is a hidden disease in Egypt, and its significance on public health has been under- estimated for decades. Road traffic accidents are the leading cause of injuries presented to hospitals in Egypt. Trauma systems… read more here.
Keywords: development trauma; challenges development; system egypt; trauma system ... See more keywords
Challenges for the development of alternative low-cost ventilators during COVID-19 pandemic in Brazil
Sign Up to like & getrecommendations! Published in 2020 at "Revista Brasileira de Terapia Intensiva"
DOI: 10.5935/0103-507x.20200075
Abstract: The COVID-19 pandemic has brought concerns to managers, healthcare professionals, and the general population related to the potential mechanical ventilators’ shortage for severely ill patients. In Brazil, there are several initiatives aimed at producing alternative… read more here.
Keywords: development; challenges development; development alternative; low cost ... See more keywords