Challenges of functional expression of complex polyketide biosynthetic gene clusters.
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DOI: 10.1016/j.copbio.2020.12.007
Abstract: Polyketide natural products are valuable sources of bioactive molecules such as nutraceuticals and pharmaceuticals. The tremendous development of the genome sequence database revealed that the majority of the biosynthetic gene clusters (BGCs) are cryptic. Activation… read more here.
Keywords: biosynthetic gene; gene clusters; challenges functional; functional expression ... See more keywords