Opportunities and challenges with G-quadruplexes as promising targets for drug design
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DOI: 10.1080/17460441.2024.2404230
Abstract: ABSTRACT Introduction G-quadruplexes (G4s) are secondary structures formed in guanine-rich regions of nucleic acids (both DNA and RNA). G4s are significantly enriched at regulatory genomic regions and are associated with important biological processes ranging from… read more here.
Keywords: challenges quadruplexes; g4s; drug; promising targets ... See more keywords