Small-molecule GLP-1 secretagogs: challenges and recent advances.
Sign Up to like & getrecommendations! Published in 2020 at "Drug discovery today"
DOI: 10.1016/j.drudis.2020.08.003
Abstract: Glucagon-like peptide-1 (GLP-1) is a potent antihyperglycemic hormone that is an alternative treatment choice for patients with type 2 diabetes mellitus (T2DM). The glucose-dependent mechanism of GLP-1 is particularly important because it does not stimulate… read more here.
Keywords: secretagogs challenges; glp secretagogs; small molecule; challenges recent ... See more keywords
Analytical Challenges and Recent Advances in Mass Spectrometry Based Lipidomics.
Sign Up to like & getrecommendations! Published in 2018 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.7b04836
Abstract: Although no internationally accepted consensus definition exists, lipids can be broadly defined as “fatty acids and their derivatives, and substances related biosynthetically or functionally to these compounds”. Lipids play critical roles as (i) the major… read more here.
Keywords: advances mass; mass spectrometry; analytical challenges; challenges recent ... See more keywords
Progress of tip-enhanced Raman scattering for the last two decades and its challenges in very recent years.
Sign Up to like & getrecommendations! Published in 2022 at "Nanoscale"
DOI: 10.1039/d2nr00274d
Abstract: Tip-enhanced Raman scattering (TERS) has recently attracted remarkable attention as a novel nano-spectroscopy technique. TERS, which provides site-specific information, can be performed on any material surface regardless of morphology. Moreover, it can be applied in… read more here.
Keywords: two decades; last two; raman scattering; tip enhanced ... See more keywords
Blending Big Data Analytics: Review on Challenges and a Recent Study
Sign Up to like & getrecommendations! Published in 2020 at "IEEE Access"
DOI: 10.1109/access.2019.2923270
Abstract: With the collection of massive amounts of data every day, big data analytics has emerged as an important trend for many organizations. These collected data can contain important information that may be key to solving… read more here.
Keywords: analytics review; data analytics; review challenges; blending big ... See more keywords
Vehicle to Pedestrian Systems: Survey, Challenges and Recent Trends
Sign Up to like & getrecommendations! Published in 2022 at "IEEE Access"
DOI: 10.1109/access.2022.3224772
Abstract: The accelerated rise of new technologies has reshaped the manufacturing industry of contemporary vehicles. Numerous technologies and applications have completely revolutionized the driving experience in terms of both safety and convenience. Although vehicles are now… read more here.
Keywords: recent trends; systems survey; vehicle pedestrian; pedestrian systems ... See more keywords
3D model of the maternal-fetal interface: challenges, recent advances and beyond.
Sign Up to like & getrecommendations! Published in 2023 at "Histology and histopathology"
DOI: 10.14670/hh-18-584
Abstract: Embryo implantation is a complex and highly coordinated process that involves an intricate network of factors establishing intimate contact at the maternal-fetal interface. Knowledge of the human implantation process is compromised by both ethical issues,… read more here.
Keywords: interface challenges; fetal interface; maternal fetal; model maternal ... See more keywords
Nanoformulations-Based Metronomic Chemotherapy: Mechanism, Challenges, Recent Advances, and Future Perspectives
Sign Up to like & getrecommendations! Published in 2023 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics15041192
Abstract: Cancer-related death is a significant health and economic burden worldwide, and some conventional chemotherapy is associated with limited effectiveness in completely curing various cancers, severe adverse effects, and destruction of healthy cells. To overcome the… read more here.
Keywords: mct; metronomic chemotherapy; nanoformulations based; mechanism challenges ... See more keywords
Challenges, Recent Advances and Perspectives in the Treatment of Human Cytomegalovirus Infections
Sign Up to like & getrecommendations! Published in 2022 at "Tropical Medicine and Infectious Disease"
DOI: 10.3390/tropicalmed7120439
Abstract: Human cytomegalovirus (HCMV) is ubiquitous worldwide and elicits global health problems. The diseases associated with HCMV are a serious threat to humans, especially for the sick, infant, elderly and immunocompromised/immunodeficient individuals. Although traditional antiviral drugs… read more here.
Keywords: hcmv infections; hcmv; human cytomegalovirus; recent advances ... See more keywords