Recent advances, approaches and challenges in targeting pathways for potential COVID-19 vaccines development
Sign Up to like & getrecommendations! Published in 2020 at "Immunologic Research"
DOI: 10.1007/s12026-020-09154-4
Abstract: During the COVID-19 pandemic in a modern era, there is a global consensus on the need for the rapid development of a vaccine against SARS-CoV-2 for effective and sustainable control. Developing these vaccines is fundamental… read more here.
Keywords: advances approaches; covid; challenges targeting; recent advances ... See more keywords
Challenges for Targeting SARS-CoV-2 Proteases as a Therapeutic Strategy for COVID-19
Sign Up to like & getrecommendations! Published in 2021 at "ACS Infectious Diseases"
DOI: 10.1021/acsinfecdis.0c00815
Abstract: Two proteases produced by the SARS-CoV-2 virus, the main protease and papain-like protease, are essential for viral replication and have become the focus of drug development programs for treatment of COVID-19. We screened a highly… read more here.
Keywords: protease; targeting sars; covid; challenges targeting ... See more keywords
Corrigendum: New approaches and challenges to targeting the endocannabinoid system
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DOI: 10.1038/nrd.2018.155
Abstract: This corrects the article DOI: 10.1038/nrd.2018.115 read more here.
Keywords: new approaches; endocannabinoid system; corrigendum new; challenges targeting ... See more keywords
Opportunities and challenges in targeting orphan nuclear receptors.
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DOI: 10.1039/d3cc00954h
Abstract: Nuclear receptor modulation enables pharmacological control of gene expression thus rendering the 48 human nuclear receptors as attractive targets for drug discovery. Several nuclear receptor ligands like glucocorticoids are approved and highly important drugs illustrating… read more here.
Keywords: nuclear receptors; nuclear receptor; challenges targeting; orphan nuclear ... See more keywords