A reporter system for enriching CRISPR/Cas9 knockout cells in technically challenging settings like patient models
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DOI: 10.1038/s41598-021-91760-9
Abstract: CRISPR/Cas9 represents a valuable tool to determine protein function, but technical hurdles limit its use in challenging settings such as cells unable to grow in vitro like primary leukemia cells and xenografts derived thereof (PDX).… read more here.
Keywords: reporter; crispr cas9; challenging settings; reporter system ... See more keywords