L-Ascorbic Acid and α-Tocopherol Reduces Hepatotoxicity Associated with Arsenic Trioxide Chemotherapy by Modulating Nrf2 and Bcl2 Transcription Factors in Chang liver Cells
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DOI: 10.1080/01635581.2018.1460676
Abstract: ABSTRACT Arsenic trioxide (As2O3) is a promising new regimen for the treatment of acute promyelocytic leukemia (APL). The induction of oxidative stress mediated by reactive oxygen species (ROS) and excessive intracellular calcium influx are the… read more here.
Keywords: chang liver; arsenic trioxide; acid tocopherol; ascorbic acid ... See more keywords