An evolutionary change in ligand
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DOI: 10.1126/science.364.6444.966-a
Abstract: Steroid Hormones Aldosterone binds to mammalian mineralocorticoid receptors to regulate electrolyte homeostasis. However, the mineralocorticoid receptor first arose in cartilaginous fish, which do not have aldosterone. Katsu et al. found that the mineralocorticoid receptor of… read more here.
Keywords: mineralocorticoid receptor; change ligand; physiology; evolutionary change ... See more keywords