Change in metabolic parameters after switching from triple regimens with tenofovir alafenamide to dolutegravir‐based dual therapy. Bi‐lipid study
Sign Up to like & getrecommendations! Published in 2022 at "HIV Medicine"
DOI: 10.1111/hiv.13432
Abstract: The use of tenofovir alafenamide (TAF) has been associated with increased cholesterol and body weight. Real‐life data on the metabolic effects of switching from a TAF‐based triple regimen to a dolutegravir (DTG)‐based two‐drug regimen (2‐DR)… read more here.
Keywords: parameters switching; change metabolic; switching triple; metabolic parameters ... See more keywords
Abstract 3143: A bioinformatic pipeline for identifying change-of-metabolic-function cancer mutations
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-3143
Abstract: Cancer arises through clonal evolution, in some cases selecting change of metabolic function (COMF) mutations that functionally alter proteins to affect cellular metabolism. COMF mutations can impart new catalytic functions that can be applied to… read more here.
Keywords: metabolic function; bioinformatic pipeline; change metabolic; comf mutations ... See more keywords