Rituximab as a Therapeutic Option for Steroid-Sensitive Minimal Change Nephrotic Syndrome in Adults.
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DOI: 10.1159/000486930
Abstract: Minimal change nephrotic syndrome (MCNS) usually responds to steroids but frequently relapses, requiring additional treatment with immunosuppressive agents. Rituximab is a chimeric murine/human monoclonal immunoglobulin G1 antibody that targets CD20, a B-cell differentiation marker. B-cell… read more here.
Keywords: change nephrotic; mcns; minimal change; nephrotic syndrome ... See more keywords
Pseudothrombus deposition accompanied with minimal change nephrotic syndrome and chronic kidney disease in a patient with Waldenström's macroglobulinemia: A case report
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DOI: 10.12998/wjcc.v7.i16.2393
Abstract: BACKGROUND Waldenström's macroglobulinemia (WM) is a rare lymphoid neoplasia, which can have renal complications. These rarely occur, and most common renal manifestations are mild proteinuria and microscopic hematuria. Herein we describe a case of WM… read more here.
Keywords: case; change nephrotic; syndrome; minimal change ... See more keywords
Tacrolimus Monotherapy after Intravenous Methylprednisolone in Adults with Minimal Change Nephrotic Syndrome.
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DOI: 10.1681/asn.2016030342
Abstract: Glucocorticoid treatment is the first choice therapy for adults with minimal change nephrotic syndrome; however, this therapy associates with many adverse effects. Tacrolimus may be an alternative to conventional glucocorticoid therapy. To investigate this possibility,… read more here.
Keywords: glucocorticoid; change nephrotic; tacrolimus; minimal change ... See more keywords
Comparison of the Efficacy and Safety of Tacrolimus and Low-Dose Corticosteroid with High-Dose Corticosteroid for Minimal Change Nephrotic Syndrome in Adults.
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DOI: 10.1681/asn.2019050546
Abstract: BACKGROUND Tacrolimus is used as a steroid-sparing immunosuppressant in adults with minimal change nephrotic syndrome. However, combined treatment with tacrolimus and low-dose steroid has not been compared with high-dose steroid for induction of clinical remission… read more here.
Keywords: dose; nephrotic syndrome; change nephrotic; minimal change ... See more keywords
Urinary Protein-to-creatinine Ratios Predict Recurrence in Pediatric and Young Adult Cases of Minimal Change Nephrotic Syndrome.
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DOI: 10.18926/amo/63207
Abstract: High-dose steroids are required for the treatment of minimal change nephrotic syndrome (MCNS), especially for episodes of recurrence. Predicting and avoiding recurrence can help reduce the steroid dose, but prediction is currently difficult. We herein… read more here.
Keywords: nephrotic syndrome; recurrence; change nephrotic; minimal change ... See more keywords