Flexible Fitting of PROTAC Concentration–Response Curves with Changepoint Gaussian Processes
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DOI: 10.1177/24725552211028142
Abstract: A proteolysis-targeting chimera (PROTAC) is a new technology that marks proteins for degradation in a highly specific manner. During screening, PROTAC compounds are tested in concentration–response (CR) assays to determine their potency, and parameters such… read more here.
Keywords: gaussian processes; concentration response; flexible fitting; changepoint gaussian ... See more keywords