Effects of changes in glycan composition on glycoprotein dynamics: example of N-glycans on insulin receptor.
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DOI: 10.1093/glycob/cwab049
Abstract: Glycosylation is among the most common post-translational modifications in proteins, although it is observed in only about 10% of all the protein structures in protein data bank (PDB). Modifications of sugar composition in glycoproteins profoundly… read more here.
Keywords: glycoprotein dynamics; glycans insulin; insulin receptor; composition ... See more keywords
Mass spectrometric profiling reveals association of N-glycan patterns with epithelial ovarian cancer progression
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DOI: 10.1177/1010428317716249
Abstract: Aberrant changes of N-glycan modifications on proteins have been linked to various diseases including different cancers, suggesting possible avenue for exploring their etiologies based on N-glycomic analysis. Changes in N-glycan patterns during epithelial ovarian cancer… read more here.
Keywords: glycan patterns; epithelial ovarian; ovarian cancer; progression ... See more keywords