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Published in 2021 at "Nature Communications"
DOI: 10.1038/s41467-020-20593-3
Abstract: High-throughput sequencing protocols such as RNA-seq have made it possible to interrogate the sequence, structure and abundance of RNA transcripts at higher resolution than previous microarray and other molecular techniques. While many computational tools have…
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Keywords:
framework;
rna seq;
changes rna;
rna transcripts ... See more keywords
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Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-23845-x
Abstract: Internal ribosome entry site (IRES) elements are RNA regions that recruit the translation machinery internally. Here we investigated the conformational changes and RNA dynamics of a picornavirus IRES upon incubation with distinct ribosomal fractions. Differential…
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Keywords:
rna dynamics;
differential shape;
ribosome dependent;
flexibility ... See more keywords
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Published in 2020 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkaa331
Abstract: Abstract RNA molecules fold into complex structures as a result of intramolecular interactions between their nucleotides. The function of many non-coding RNAs and some cis-regulatory elements of messenger RNAs highly depends on their fold. Single-nucleotide…
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Keywords:
induced changes;
mutation induced;
structure;
changes rna ... See more keywords