Articles with "changes transcriptome" as a keyword



O017 Dupuytren's disease (DD): WNT4 knockdown in normal skin fibroblasts leads to ‘DD-like’ changes in the transcriptome

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Published in 2023 at "British Journal of Surgery"

DOI: 10.1093/bjs/znad101.017

Abstract: Dupuytren's disease (DD), a fibro-proliferative disorder of unknown aetiology, affects the palm and is characterised by progressive fibrosis, thickening of palmar fascia, and excess collagen deposition. Patients present with nodules, causing flexion deformity in ∼50%,… read more here.

Keywords: like changes; skin; changes transcriptome; skin fibroblasts ... See more keywords