ATP-Responsive Liposomes via Screening of Lipid Switches Designed to Undergo Conformational Changes upon Binding Phosphorylated Metabolites.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.2c00191
Abstract: Liposomal delivery vehicles can dramatically enhance drug transport. However, their clinical application requires enhanced control over content release at diseased sites. For this reason, triggered release strategies have been explored, although a limited toolbox of… read more here.
Keywords: lipid switches; conformational changes; designed undergo; changes upon ... See more keywords
Analysis and prediction of protein folding energy changes upon mutation by element specific persistent homology
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DOI: 10.1093/bioinformatics/btx460
Abstract: Motivation Site directed mutagenesis is widely used to understand the structure and function of biomolecules. Computational prediction of mutation impacts on protein stability offers a fast, economical and potentially accurate alternative to laboratory mutagenesis. Most… read more here.
Keywords: protein; topology; protein stability; upon mutation ... See more keywords