Inhibitory effects of retigabine, a Kv7 channel activator, on mechanosensitive primary bladder afferent activities and nociceptive behaviors in rats
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DOI: 10.1002/nau.22920
Abstract: Kv7 voltage‐gated potassium channels have been suggested to modulate mechano‐afferent transduction and nociception in the bladder. We investigated the effects of retigabine, a Kv7 channel activator, on rhythmic bladder contractions (RBCs), and single‐unit afferent activities… read more here.
Keywords: channel activator; bladder; retigabine kv7; kv7 channel ... See more keywords
Abstract 297: Therapeutic Effects of SK Channel Activator on Cardioprotection in the Setting of Cardioplegic Ischemia-Reperfusion and Cardiopulmonary Bypass
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DOI: 10.1161/res.125.suppl_1.297
Abstract: Background: Inactivation of small-conductance calcium-activated potassium (SK) channels contributes to coronary microvascular dysfunction in patients after cardioplegic arrest, cardiopulmonary bypass (CP/CPB) and cardiac surgery. SK-channel activation is cardioprotective in rodent isolated heart model of myocardial… read more here.
Keywords: channel activator; cardiopulmonary bypass; reperfusion; cardioplegic ischemia ... See more keywords