Articles with "channel block" as a keyword



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Effect of Channel Block on Multiple Coherence Resonance Induced by Time Delay in Adaptive Neuronal Networks with Spike-Timing-Dependent Plasticity

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Published in 2018 at "Fluctuation and Noise Letters"

DOI: 10.1142/s0219477518500360

Abstract: In this paper, we study effect of channel block (CB) on multiple coherence resonance (MCR) in adaptive scale-free Hodgkin–Huxley neuronal networks with spike-timing-dependent plasticity (STDP). It is found that potassium CB suppresses MCR, but sodium… read more here.

Keywords: channel block; multiple coherence; effect; effect channel ... See more keywords
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Tricyclic Antidepressant Structure-Related Alterations in Calcium-Dependent Inhibition and Open-Channel Block of NMDA Receptors

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Published in 2022 at "Frontiers in Pharmacology"

DOI: 10.3389/fphar.2021.815368

Abstract: N-methyl-D-aspartate receptors (NMDARs) are an essential target for the analgetic action of tricyclic antidepressants (TCAs). Their therapeutic blood concentrations achieve 0.5–1.5 μM, which, however, are insufficient to cause in vitro the open-channel block known as… read more here.

Keywords: dependent inhibition; open channel; channel block;