Articles with "channel kv1" as a keyword



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Interaction of the Inhibitory Peptides ShK and HmK with the Voltage-Gated Potassium Channel KV1.3: Role of Conformational Dynamics

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Published in 2023 at "Journal of chemical information and modeling"

DOI: 10.1021/acs.jcim.2c01237

Abstract: Peptide toxins that adopt the ShK fold can inhibit the voltage-gated potassium channel KV1.3 with IC50 values in the pM range and are therefore potential leads for drugs targeting autoimmune and neuroinflammatory diseases. Nuclear magnetic… read more here.

Keywords: gated potassium; voltage gated; kv1; channel kv1 ... See more keywords