Paradoxical hyperexcitability from NaV1.2 sodium channel loss in neocortical pyramidal cells.
Sign Up to like & getrecommendations! Published in 2021 at "Cell reports"
DOI: 10.1016/j.celrep.2021.109483
Abstract: Loss-of-function variants in the gene SCN2A, which encodes the sodium channel NaV1.2, are strongly associated with autism spectrum disorder and intellectual disability. An estimated 20%-30% of children with these variants also suffer from epilepsy, with… read more here.
Keywords: channel loss; sodium channel; pyramidal cells; loss ... See more keywords
0.058 mm2 13 Gbit/s inductorless analogue equaliser with low-frequency equalisation compensating 15 dB channel loss
Sign Up to like & getrecommendations! Published in 2018 at "Electronics Letters"
DOI: 10.1049/el.2017.3853
Abstract: An inductorless 13 Gbit/s analogue equaliser with an additional low-frequency equalisation (LFEQ) to counter the low-frequency channel losses is presented. An active feedback topology for the proposed equaliser together with negative capacitance circuit is used… read more here.
Keywords: frequency; analogue equaliser; channel loss; low frequency ... See more keywords