The water channel protein aquaporin 1 regulates cellular metabolism and competitive fitness in a global fungal pathogen Cryptococcus neoformans
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DOI: 10.1111/1758-2229.12527
Abstract: In this study, an aquaporin protein, Aqp1, in Cryptococcus neoformans, which can lead either saprobic or parasitic lifestyles and causes life-threatening fungal meningitis was identified and characterized. AQP1 expression was rapidly induced (via the HOG… read more here.
Keywords: fungal pathogen; cryptococcus neoformans; competitive fitness; water channel ... See more keywords
Two‐pore channel protein TPC1 is a determining factor for the adaptation of proximal tubular phosphate handling
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DOI: 10.1111/apha.13914
Abstract: Two‐pore channels (TPCs) constitute a small family of cation channels expressed in endo‐lysosomal compartments. TPCs have been characterized as critical elements controlling Ca2+‐mediated vesicular membrane fusion and thereby regulating endo‐lysosomal vesicle trafficking. Exo‐ and endocytotic… read more here.
Keywords: channel protein; tpc1 determining; two pore; protein tpc1 ... See more keywords
Interactions between Artificial Channel Protein, Water Molecules, and Ions Based on Theoretical Approaches
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DOI: 10.3390/sym14040691
Abstract: Contemporary techniques of molecular modeling allow for rational design of several specific classes of artificial proteins. Transmembrane channels are among these classes. A recent successful synthesis of self-assembling, highly symmetrical 12- or 16-helix channels by… read more here.
Keywords: water molecules; molecules ions; channel protein; artificial channel ... See more keywords