Recording Channelrhodopsin-Evoked Field Potentials and Startle Responses from Larval Zebrafish.
Sign Up to like & getrecommendations! Published in 2021 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-0830-2_13
Abstract: Zebrafish are an excellent model organism to study many aspects of vertebrate sensory encoding and behavior. Their escape responses begin with a C-shaped body bend followed by several swimming bouts away from the potentially threatening… read more here.
Keywords: channelrhodopsin evoked; field potentials; chr2; channelrhodopsin ... See more keywords
Kinetic profiles of photocurrents in cells expressing two types of channelrhodopsin genes.
Sign Up to like & getrecommendations! Published in 2018 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2018.01.149
Abstract: Channelrhodopsin-2 (ChR2), a light-activated cation-selective ion channel, has been widely used as a tool in optogenetic research. ChR2 is specifically sensitive to wavelengths less than 550 nm. One of the methods to expand the sensitivity of… read more here.
Keywords: expressing two; cells expressing; kinetic profiles; channelrhodopsin ... See more keywords
Long-term expression of melanopsin and channelrhodopsin causes no gross alterations in the dystrophic dog retina
Sign Up to like & getrecommendations! Published in 2017 at "Gene Therapy"
DOI: 10.1038/gt.2017.63
Abstract: Several preclinical studies have investigated the potential of algal channelrhodopsin and human melanopsin as optogenetic tools for vision restoration. In the present study, we assessed the potentially deleterious effects of long-term expression of these optogenes… read more here.
Keywords: melanopsin; long term; channelrhodopsin; term expression ... See more keywords
Channelrhodopsin-mediated optogenetics highlights a central role of depolarization-dependent plant proton pumps
Sign Up to like & getrecommendations! Published in 2020 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2005626117
Abstract: Significance People for centuries are puzzled how living creatures like plants sense their environment. Plants employ electrical signals to communicate a cue-dependent local status between plants cells and organs. As a first response to biotic… read more here.
Keywords: plant; channelrhodopsin; membrane potential; depolarization ... See more keywords
Tailoring baker’s yeast Saccharomyces cerevisiae for functional testing of channelrhodopsin
Sign Up to like & getrecommendations! Published in 2023 at "PLOS ONE"
DOI: 10.1371/journal.pone.0280711
Abstract: Channelrhodopsin 2 (ChR2) and its variants are the most frequent tools for remote manipulation of electrical properties in cells via light. Ongoing attempts try to enlarge their functional spectrum with respect to ion selectivity, light… read more here.
Keywords: growth; baker yeast; channelrhodopsin; yeast ... See more keywords
The Mechanism of the Channel Opening in Channelrhodopsin-2: A Molecular Dynamics Simulation
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24065667
Abstract: Channelrhodopsin-2 (ChR2) has been one of the most important objects in the study of optogenetics. The retinal chromophore molecule absorbs photons and undergoes an isomerization reaction, which triggers the photocycle, resulting in a series of… read more here.
Keywords: channel opening; mechanism; molecular dynamics; channelrhodopsin ... See more keywords