Ion Channels in Cancer: Are Cancer Hallmarks Oncochannelopathies?
Sign Up to like & getrecommendations! Published in 2018 at "Physiological reviews"
DOI: 10.1152/physrev.00044.2016
Abstract: Genomic instability is a primary cause and fundamental feature of human cancer. However, all cancer cell genotypes generally translate into several common pathophysiological features, often referred to as cancer hallmarks. Although nowadays the catalog of… read more here.
Keywords: channels cancer; ion channels; ion channel; cancer hallmarks ... See more keywords
Therapeutic potential of TRPM8 channels in cancer treatment
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2023.1098448
Abstract: Cancer is a multifactorial process associated with changes in signaling pathways leading to cell cycle variations and gene expression. The transient receptor potential melastatin 8 (TRPM8) channel is a non-selective cation channel expressed in neuronal… read more here.
Keywords: potential trpm8; therapeutic potential; channels cancer; trpm8 channels ... See more keywords