Faulty TRPM4 channels underlie age-dependent cerebral vascular dysfunction in Gould syndrome
Sign Up to like & getrecommendations! Published in 2023 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2217327120
Abstract: Significance Cerebral small vessel diseases (cSVDs) are a group of related idiopathic and familial pathologies that cause stroke, intracerebral hemorrhage (ICH), and cognitive decline. The underlying mechanisms are poorly understood, and no effective treatment options… read more here.
Keywords: dependent cerebral; age dependent; underlie age; faulty trpm4 ... See more keywords
TRPC1 channels underlie stretch-modulated sarcoplasmic reticulum calcium leak in cardiomyocytes
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2022.1056657
Abstract: Transient receptor potential canonical 1 (TRPC1) channels are Ca2+-permeable ion channels expressed in cardiomyocytes. An involvement of TRPC1 channels in cardiac diseases is widely established. However, the physiological role of TRPC1 channels and the mechanisms… read more here.
Keywords: trpc1; channels underlie; trpc1 channels; sarcoplasmic reticulum ... See more keywords