Conserved S/T Residues of the Human Chaperone DNAJB6 Are Required for Effective Inhibition of Aβ42 Amyloid Fibril Formation.
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DOI: 10.1021/acs.biochem.8b00353
Abstract: The human molecular chaperone DNAJB6, an oligomeric protein with a conserved S/T-rich region, is an efficient suppressor of amyloid fibril formation by highly aggregation-prone peptides such as the Aβ and polyQ peptides associated with Alzheimer's… read more here.
Keywords: fibril formation; amyloid fibril; chaperone dnajb6; formation ... See more keywords