The yeast molecular chaperone, Hsp104, influences transthyretin aggregate formation
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DOI: 10.3389/fnmol.2022.1050472
Abstract: Patients with the fatal disorder Transthyretin Amyloidosis (ATTR) experience polyneuropathy through the progressive destruction of peripheral nervous tissue. In these patients, the transthyretin (TTR) protein dissociates from its functional tetrameric structure, misfolds, and aggregates into… read more here.
Keywords: yeast molecular; aggregate populations; chaperone; molecular chaperone ... See more keywords