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Published in 2019 at "Nature Biomedical Engineering"
DOI: 10.1038/s41551-019-0367-6
Abstract: A computationally designed small molecule inhibits the replication of prion-protein aggregates and ameliorates neurological symptoms in mouse and non-human-primate models of transmissible spongiform encephalopathy.
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Keywords:
prion diseases;
designer chaperone;
prion;
chaperone prion ... See more keywords